What are the mitral valve prolapse causes and risk factors?
What are the mitral valve prolapse causes? Do you know the risk factors of MVP? According to medical professionals, there are a number of known causes and risk factors, starting with age and gender.
While the prolapse condition affects females and males of all ages, it appears to be more prevalent in women aged 20+. Men are at greater risk of complications, though, particularly those over 50. Race and ethnicity may be risk factors.
Incidences of MVP are difficult to calculate. However, health authorities estimate that between two and eight percent of the global population are living with mitral valve prolapse. This makes Barlow’s Syndrome one of the most common heart valve disorders. Mitral prolapse can be symptomatic or asymptomatic. Approximately 40 percent of sufferers experience dysautonomia symptoms.
Are there any other mitral valve prolapse risk factors?
Yes, there are various other risk factors and potential mitral valve prolapse causes. MVP tends to be hereditary, passing down to offspring. There is a tendency for the affected family members to be tall and have a low body mass index and straight backs. They usually also have long fingers, arm spans greater than their height, and hypermobile joints (joints that stretch farther than normal).
The reasons for this particular body type prevalence among people with mitral prolapse are not clear to researchers. Connective tissue disorders seem to be behind the similarities. People with Marfan Syndrome, for example, will typically display such features and are more inclined to have a prolapse. MVP also occurs more often in those with Ehlers-Danlos Syndrome and Osteogenesis Imperfecta.
Lupus, Pseudoxanthoma Elasticum, Ebstein’s Anomaly, Scoliosis, and Kyphosis may also qualify as risk factors and underlying mitral valve prolapse causes. Other diseases associated with MVP include Pectus Excavatum, Graves’ Disease, PKD, Large Atrial Septal Defect, and Collagen Vascular Disease. X-linked Duchenne, hypotension, CAD, and tricuspid valve prolapse have also been linked to MVP.
What causes mitral valve prolapse?
The primary cause of mitral valve prolapse is myxomatous degeneration. This medical term refers to the enlargement, thickening, and redundancy of one or more mitral valve leaflets and/or chordae tendineae due to a build-up of proteoglycans. This generally occurs over time as a person ages. How and why it occurs is not fully understood by experts, although there are some theories.
Untreated or undertreated Rheumatic Fever is yet another of the mitral valve prolapse causes. This is an inflammatory disease that sometimes occurs after a Strep Throat infection or Scarlet Fever and mainly affects children. Rheumatic Fever can damage the mitral valve by scarring the leaflets, leading to mitral valve regurgitation, or by thickening them, causing mitral valve stenosis – or both.
Myocardial infarctions (heart attacks) can also damage the heart and the mitral valve, as can certain medications. Ergotamine and other migraine medications have been linked to heart valve disease. Drugs like Pergolide (which in some countries is used to treat Parkinson’s Disease), Dexfenfluramine, and Fenfluramine (appetite suppressants) also increase the likelihood of MVP developing.